1h 25m
Louis Roller
22 Mar 2018

Pharmacokinetics and Pharmacodynamics

This Course reviews pharmacokinetic concepts related to how medicines act on the human body, as well as pharmacokinetic concepts that explore how the human body acts on medicines.


Use your understanding of the relationship between pharmacokinetics and pharmacodynamics to prevent adverse medication events that may impact on patient outcomes


Identify the processes through which the human body absorbs, distributes, metabolises and eliminates medicines in order to educate patients on effective medication management


Link the concepts of pharmacodynamics and pharmacokinetics with best clinical practice in order to enhance delivery of care


Louis Roller

Associate Professor Louis Roller has been an academic at the Faculty of Pharmacy and Pharmaceutical Sciences Monash University for over 50 years. He was on the Pharmacy Board of Victoria for 22 years and has significantly contributed to many editions of various pharmaceutical compendia, including the Therapeutic Guidelines, particularly the Antibiotic Guidelines. He is the author of hundreds of scientific and professional articles and has a passion for evidence-based knowledge. He lectures to pharmacists, medical practitioners, nurses, podiatrists, and optometrists on a variety of therapeutic topics, particularly antibiotics, as well as giving many talks to the University of the Third Age on various medication-related issues. As at the end of April, he had delivered 42 talks to U3A Stonnington and an equivalent number to other U3A groups. With Dr Jenny Gowan, over the last 20 years, he has written articles on disease state management in the Australian Journal of Pharmacy. In 2012, he was made a life member of the Australasian Pharmaceutical Sciences Association and, in 2014, he was awarded the life-long achievement award of the Pharmaceutical Society of Australia.


Beverly Salt17 Aug 2018
learned more knowledge. found interesting

Tanya Volzke11 Jul 2018
Concepts were presented to be easily understood.

Elizabeth Jane Abbott05 Jul 2018
Very good.

Michelle Cooke30 Jun 2018
very good presentation

Cecil Maverick Quimio27 Jun 2018
good review and vla

Soumyamol Binesh16 Jun 2018

Hannah Charles13 Jun 2018
Very good lecture, informative and packed full of useful information

Georgia Jones06 Jun 2018
very informative

carin newman04 Jun 2018
I felt the educator was informative and fantastic in providing information about medications and the effect it has on the body.

Valerie Courreges30 May 2018
Very detailed and informative

Mark James30 May 2018

Ruth Curtis30 May 2018
Good resource.

Maria-Lisa Andonela Cravo30 May 2018

Eden Kersten30 May 2018
Was good to refreshed my memory and was easy to do.

justine lopez29 May 2018
Very informative and fairly easily uunderstood for a complex matter of information

Gillian Carne29 May 2018
Heavy but informative

Claire Jacobs29 May 2018
This video was very helpful and interesting.

Nicole Ferreira28 May 2018
Very comprehensive

Pam Patch26 May 2018
Very informative. Thank you

Katherine Hepworth26 May 2018

Very good presenter.

Louise Morosi24 May 2018
This was very interesting if not a bit complex for an EN new grad, was happy to glean a deeper understand of how stuff works.

Krishna paudel24 May 2018
excellent lesson

Babaldeep Singh23 May 2018
Simple, Detailed information in easy and simple way.

Sabbiah jang23 May 2018
Very helpful

Phoebe tsourdalakis23 May 2018

Naomi Johnston23 May 2018
The educator spoke well very engaging and easy to listen to and absorb the education.

Melissa kendon21 May 2018
Very interesting and Informative

Linda Pye21 May 2018
I found the mix of visuals helpful to understand the concepts

Amala Thomas20 May 2018
Really good

Linda Ann wilson17 May 2018

Jinju Rajeev16 May 2018

Catherine therese Simpson16 May 2018
that was interesting

Harsimrat Kaur15 May 2018
good learning topic

Joanne Holloway14 May 2018
To be honest this education was a little bit harder to follow than most but I found that I was able to relate it to my renal nursing.

Efstathia Stanitsas14 May 2018
Very interesting lecture.

Lisa Lising Reyes12 May 2018
Excellent learning tool

Emelye Coenraad12 May 2018
Really easy to understand information.

Mayumi Nakazawa11 May 2018

Lin Jiang10 May 2018

Jane Wilson09 May 2018
educator engaging recommend to other health professionals

Angelo Carlo Rontos09 May 2018
the cpd was very helpful and informative

Cheryl Carpenter08 May 2018
Very good

Caiping Jiang08 May 2018

Kerry Todero08 May 2018
Very interesting and easy to follow.

Nicole Gregory08 May 2018
For anyone who has ever had an issue trying to get their head around half lives, creatinine clearance measurements and other pharmacology. Very succinct delivery of important information for all health professionals.

Kirsten Wynter04 May 2018
Easy to follow and very informative.

Therese Martin03 May 2018
I have learned a greater understanding of medications, and their interactions on the human body.

Pooja Saini02 May 2018
very good

Jacinta Egoroff02 May 2018
Very informative, but better to watch if you have some background education/knowledge on the matter,

Leone Knight01 May 2018
Detailed but important information.

Susan Cynthia Barnes29 Apr 2018
I found this resource informative and enlightening.

Lavinia Luce Bellion-Dwyer28 Apr 2018
I found this learning to be a bit dry and think it needs an update and a little more knowledge to someone who is not very familiar with this subject.

Carolyn Buchholz26 Apr 2018
quite a lot of small words and calculations needed.

Ma. Christina Cate24 Apr 2018

Bimaldeep Sidhu24 Apr 2018
very informative and interesting

siobhan perkins23 Apr 2018
Very informative.

Lisa Maree Willmott23 Apr 2018
I really enjoyed increasing my understanding of this subject.

APEL MAHMUD22 Apr 2018
Its a very informative session

mamta mamta22 Apr 2018
it was good source to review the previous knowledge.

Julie Shakespeare21 Apr 2018
Excellent presentation

Josephine Clark20 Apr 2018
This is a reasonably boring subject for me, but I found it was explained very well & in a manner where I had some understanding of subject.

Rebecca Farley20 Apr 2018
I found this education very helpful and easy to understand.

Adam Spinks19 Apr 2018
Excellent resource for all nurses and health professionals who may need to answer questions relating to medicines.

Harpuneet Kaur19 Apr 2018
Excellent work

Mary Grace Narvadez18 Apr 2018
This is one of the best videos I have watched on AusMed. I enjoyed every minute of it.

Queen Elthan Tatad18 Apr 2018
very informative!

Joanne Kneebone17 Apr 2018
I enjoyed the use of animation to explain the effects of medicine on the body

Daryl Stuart17 Apr 2018
Very relevant and interesting.

Helen Marsham17 Apr 2018
A great course which has increased my understanding of medicines and how the body deals with them and the impact it has when assessing the patients response to medication

Jotara Watson16 Apr 2018
Clear and concise with plenty of visual graphics that enhanced learning.

Peter Michael Osbucan Olat15 Apr 2018
Very informative

Nida Deligero Lagunay12 Apr 2018
Very helpful and useful resources.

Nancy Gomes11 Apr 2018


Sophia Kim10 Apr 2018
Very useful education video.

Amanpreet Kaur10 Apr 2018

Cathy Makamet Loleni Silailai09 Apr 2018
The CPD activity is very educational and relevant to me a student nurse and I would recommend this E-learning to all health professionals.

Elyssa Wedd09 Apr 2018
This online video course was so informative and was easy to comprehend, that it has enabled to feel more informed on the effects of pharmacokinetics and pharmacodynamics.

Meryl Gay07 Apr 2018
Good, clear tutorial.

Andre Tay06 Apr 2018
Good review and well presented.

Casey Casey06 Apr 2018
Very informative.

Cheryl Gillam05 Apr 2018
This made for an interesting CPD. Speaker was very informed on the topic and delivered information clearly and precise.


Adrienne Hokin02 Apr 2018
A great learning lecture that I recommend to everyone.

Tracey Laberge31 Mar 2018
I gained a better understanding of how drugs work in the body and how the works with drugs.

Troy McIntosh31 Mar 2018
Thoroughly enjoyed this content. It has improved my understanding by delivering the subject in a non-flowery manner.

Lauren Marriott30 Mar 2018
Excellent...very interactive

Jocelyn Broadbent30 Mar 2018
An excellent resource for health professionals.

Ann Trebilcock30 Mar 2018
Very interesting information, it built on my existing knowlege and gave me more information on which to make informed decisions.

Citti Taranto28 Mar 2018
Learning these topics it brings safer and more effective therapeutic management of drugs in an individual patient

Louise Macfarlane28 Mar 2018
I strongly advise all RNs to review this resource to provide a greater understanding of medicines.

Wendy Merritt27 Mar 2018
Easy to understand, enjoyed it!

Chris Wilson27 Mar 2018
Well explained and clear. A good refresher and well worth doing

Kasha Wiencierz27 Mar 2018
Amazing session, very informative!

Andrew Markula27 Mar 2018
Very valuable information.

Michele Selby26 Mar 2018

Judith Carlsson04 Dec 2017
This was a very informative talk. I really enjoyed the way it was presented.

Course Overview

Topics include:

  • An overview of pharmacokinetics (PK) and pharmacodynamics (PD)
  • The ADE (absorption, distribution and excretion) curve and the implications of the therapeutic range
  • A definition of bioavailability and its effects on medicine quality, brand substitution and the use of generic medications
  • How therapeutic medicine monitoring is used, how protein binding influences distribution, and how hepatic metabolic elimination and reabsorption occur
  • Methods of medicine elimination, including renal elimination, and factors that affect elimination and reabsorption
  • Multiple dose regimes, making reference to the definitions of peak and trough levels, loading dose and steady state
  • Pharmacogenomics (personalised medicine) and genetic variability in response to medicines
  • Pharmacokinetic medicine-medicine interactions

Target audience

All healthcare professionals, particularly RNs, medication-endorsed ENs and Nurse Practitioners working in a variety of specialities.


Review the basic concepts relating to how medicines work on the human body, and the importance of bioavailability, half-life, medicine-medicine interactions, and peak and trough levels in therapy.


Pharmacological therapy and medication administration is fundamental in professional nursing practice. It involves a strong patient and ethical focus, as well as ongoing education in order to have a positive impact on patient outcomes. However, many of the principles underlying how medicines work are often difficult to comprehend. As safe administration of medicines is a priority, it is essential that nurses continue to demonstrate knowledge of the concepts and methods of medicine absorption, distribution and elimination in their patient care.

Health professionals in Australia that are registered with AHPRA are required to obtain continuing professional development (CPD) hours/points each year that relates to their context of practice, in order to comply with mandatory regulatory requirements.